Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278921 | 0.78 | SLC15A1 (0.45) | SLC15A1EPHX1ACHERAB9AMAPT | |
| SCHEMBL9809028 | 0.77 | CTSK (0.36) | CYP1A2CYP2C19 | |
| SCHEMBL10586050 | 0.76 | SMN1; SMN2 (0.38) | EPHX1ACHERAB9AMAPTNPSR1 | |
| SCHEMBL7609352 | 0.73 | EPHX1 (0.48) | EPHX1ACHERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL122568 | 0.73 | ALDH1A1 (0.47) | EPHX1ACHERAB9AMAPTNPSR1 | |
| SCHEMBL590532 | 0.72 | EPHX1 (0.59) | EPHX1ACHERAB9AMAPTNPSR1 | |
| SCHEMBL9809030 | 0.72 | METAP2 (0.37) | ALDH1A1CYP2C19 | |
| SCHEMBL29216493 | 0.72 | EPHX1 (0.47) | EPHX1ACHERAB9AMAPTNPSR1 | |
| SCHEMBL7288121 | 0.71 | CTSK (0.49) | SLC15A1RAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL112501 | 0.69 | MARS1 (0.43) | HPGDALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322633-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-07-05 | — | — | EP | disclosed |