SCHEMBL2584804

SCHEMBL2584804

CC(C)(C)OC(=O)[C@H](N)COCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.54
PPARA Q07869 2/20 0.53
LTA4H P09960 1/20 0.53
CTSS P25774 1/20 0.50
PPARG P37231 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
CA1 P00915 3/20 0.45
TACR1 P25103 2/20 0.45
SLC7A5 Q01650 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
KLK7 P49862 1/20 0.44
KLK5 Q9Y337 1/20 0.44
SYK P43405 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4220523 1.00 SLC1A1 (0.54) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL7338978 1.00 SLC1A1 (0.54) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL7380413 0.89 PPARA (0.49) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL5860435 0.89 PPARA (0.49) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL29447511 0.86 LTA4H (0.57) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL4220364 0.86 LTA4H (0.51) SLC1A1PPARALTA4HCTSSL3MBTL1
SCHEMBL23541264 0.84 PPARA (0.54) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL487462 0.84 PPARA (0.54) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL487460 0.84 PPARA (0.54) SLC1A1PPARALTA4HCTSSPPARG
SCHEMBL3732892 0.84 PPARA (0.57) SLC1A1PPARALTA4HCTSSPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111295373-B Compositions and methods for treating brain injury 阿泽凡药物公司 2024-12-10 CN disclosed
US-20240115553-A1 COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY AZEVAN PHARMACEUTICALS, INC. (US) 2024-04-11 US disclosed
CN-116327950-A Use of a composition for the treatment of neuropsychiatric symptoms of neurodegenerative diseases 阿泽范药品公司 2023-06-27 CN disclosed
CN-116139282-A Compositions and methods for treating neurodegenerative diseases 阿泽范药品公司 2023-05-23 CN disclosed
US-20230123729-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES AZEVAN PHARMACEUTICALS INC (US) 2023-04-20 US disclosed
US-11628160-B2 Compositions and methods for treating brain injury AZEVAN PHARMACEUTICALS, INC. (US) 2023-04-18 US disclosed
CN-106459021-B Compositions and methods for treating neurodegenerative diseases 阿泽范药品公司 2023-04-07 CN disclosed
EP-3122743-B1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES AZEVAN PHARMACEUTICALS INC (US) 2022-11-09 EP disclosed
US-11319306-B2 Compositions and methods for treating neurodegenerative diseases AZEVAN PHARMACEUTICALS, INC. (US) 2022-05-03 US disclosed
US-10953001-B2 Methods for treating post traumatic stress disorder AZEVAN PHARMACEUTICALS, INC. (US) 2021-03-23 US disclosed
US-20080113959-A1 {Beta}-Lactamyl vasopression V1a antagonists and methods of use AZEVAN PHARMACEUTICALS, INC. (US) 2008-05-15 US disclosed
US-20080090797-A1 {Beta}-Lactamyl vasopression V1a antagonists and methods of use AZEVAN PHARMACEUTICALS, INC. (US) 2008-04-17 US disclosed
EP-1910346-A2 BETA-LACTAMYL PHENYLALANINE, CYSTEINE, AND SERINE VASOPRESSIN ANTAGONIST Azevan Pharmaceuticals, Inc. (US) 2008-04-16 EP disclosed
US-20080033165-A1 [Beta]-Lactamyl Vasopressin V1a Antagonists and Methods of Use KOPPEL GARY A 2008-02-07 US disclosed
US-7268125-B2 β-lactamyl vasopressin V1a antagonists AZEVAN PHARMACEUTICALS, INC. (US) 2007-09-11 US disclosed
WO-2007011878-A2 BETA-LACTAMYL PHENYLALANINE, CYSTEINE, AND SERINE VASOPRESSIN ANTAGONISTS AZEVAN PHARMACEUTICALS, INC. (US) 2007-01-25 WO disclosed
US-7119083-B2 β-Lactamyl vasopressin V1a Antagonists AZEVAN PHARMACEUTICALS, INC. (US) 2006-10-10 US disclosed
US-20060217364-A1 Beta-lactamyl vasopressin V1a antagonists NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-09-28 US disclosed
CN-1606554-A Beta-lactam vasopressin V1a Antagonists SERENIX PHARMACEUTICALS LLC (US) 2005-04-13 CN disclosed
US-20040266750-A1 Beta-lactamyl vasopressin v1aantagonists AZEVAN PHARMACEUTICALS, INC. 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115553-A1 COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY FABP7, PYGB, CHAT SLC1A1 1024/4885PPARA 2116/4885LTA4H 927/4885
US-20080090797-A1 {Beta}-Lactamyl vasopression V1a antagonists and methods of use AVPR1A, AVPR2, AVPR1B SLC1A1 181/4885PPARA 1803/4885LTA4H 380/4885
US-20060217364-A1 Beta-lactamyl vasopressin V1a antagonists AVPR1A, AVPR2, AVPR1B SLC1A1 628/4885PPARA 1081/4885LTA4H 542/4885
US-10953001-B2 Methods for treating post traumatic stress disorder GPX4, CRH, TXN SLC1A1 438/4885PPARA 2002/4885LTA4H 458/4885
US-11319306-B2 Compositions and methods for treating neurodegenerative diseases HTT, AVPR2, AVPR1B SLC1A1 337/4885PPARA 478/4885LTA4H 1747/4885
US-20230123729-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES HTT, AVPR2, AVPR1B SLC1A1 337/4885PPARA 478/4885LTA4H 1747/4885
US-20080113959-A1 {Beta}-Lactamyl vasopression V1a antagonists and methods of use AVPR1A, AVPR2, AVPR1B SLC1A1 181/4885PPARA 1803/4885LTA4H 380/4885
US-11628160-B2 Compositions and methods for treating brain injury FABP7, PYGB, CHAT SLC1A1 1024/4885PPARA 2116/4885LTA4H 927/4885
US-20080033165-A1 [Beta]-Lactamyl Vasopressin V1a Antagonists and Methods of Use AVPR2, AVPR1A, AVPR1B SLC1A1 829/4885PPARA 963/4885LTA4H 324/4885
US-20040266750-A1 Beta-lactamyl vasopressin v1aantagonists AVPR1A, AVPR2, AVPR1B SLC1A1 439/4885PPARA 1915/4885LTA4H 543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.