Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HA1 | P13674 | 3/20 | 0.58 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.58 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424800 | 0.88 | KDM4E (0.48) | P4HA1P4HTMNISCHLDHACYP1A2 | |
| SCHEMBL14496851 | 0.77 | NISCH (0.62) | NISCHCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5879537 | 0.77 | NISCH (0.45) | NISCHCYP1A2KDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3900407 | 0.76 | NISCH (0.61) | NISCHCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29397057 | 0.75 | P4HTM (1.00) | P4HA1P4HTMLDHACYP1A2MIF | |
| SCHEMBL29683317 | 0.75 | P4HTM (1.00) | P4HA1P4HTMLDHACYP1A2MIF | |
| SCHEMBL68560 | 0.75 | P4HTM (1.00) | P4HA1P4HTMLDHACYP1A2MIF | |
| SCHEMBL5879534 | 0.75 | NISCH (0.43) | NISCHCYP1A2KDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8204973 | 0.74 | NISCH (0.64) | NISCHKDM4EALDH1A1LMNA | |
| SCHEMBL4726421 | 0.73 | NISCH (0.56) | NISCHCYP1A2KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |