Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279147 | 0.77 | P4HA1 (0.58) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL24405932 | 0.71 | NISCH (0.45) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL5879534 | 0.70 | NISCH (0.43) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL4726421 | 0.69 | NISCH (0.56) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL10424800 | 0.68 | KDM4E (0.48) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL20576848 | 0.67 | OXTR (0.41) | KDM4EALDH1A1ALOX15 | |
| SCHEMBL27663663 | 0.67 | GABRP (0.48) | KDM4EALDH1A1 | |
| SCHEMBL5879623 | 0.66 | NISCH (0.51) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL2767198 | 0.65 | KCNH2 (0.37) | KDM4EALDH1A1ALOX15 | |
| SCHEMBL17544162 | 0.65 | OXTR (0.37) | KDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |