Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | WDR5 | P61964 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514295 | 0.81 | NISCH (0.56) | NISCHCYP1A2PPARGALDH1A1LMNA | |
| SCHEMBL5879623 | 0.76 | NISCH (0.51) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL7279147 | 0.75 | P4HA1 (0.58) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL23930179 | 0.71 | CYP11B1 (0.55) | CYP1A2HPGDSCYP3A4LMNA | |
| SCHEMBL5879537 | 0.70 | NISCH (0.45) | NISCHCYP1A2KDM4EPDCD1LG2CD274 | |
| SCHEMBL1936166 | 0.70 | NISCH (0.58) | NISCHPPARGLMNA | |
| SCHEMBL13732044 | 0.69 | NAMPT (0.56) | CYP1A2KDM4EWDR5ALDH1A1CYP3A4 | |
| SCHEMBL3260324 | 0.68 | NISCH (0.60) | NISCHPPARGLMNA | |
| SCHEMBL17090962 | 0.68 | CYP11B1 (0.54) | — | |
| SCHEMBL4726421 | 0.67 | NISCH (0.56) | NISCHCYP1A2KDM4EPDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |