Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877666 | 0.81 | HIF1A (0.52) | SSTR4HPGDHIF1AKDM4EALDH1A1 | |
| SCHEMBL11952613 | 0.80 | SSTR4 (0.41) | SSTR4HPGDTSHRHIF1AGABRA1 | |
| SCHEMBL10366394 | 0.78 | HIF1A (0.38) | SSTR4HPGDTSHRHIF1AGABRA1 | |
| SCHEMBL8035974 | 0.77 | AOC2 (0.40) | SSTR4HPGDTSHRHIF1AGABRA1 | |
| SCHEMBL12911435 | 0.73 | MAOA (0.41) | SSTR4HPGDTSHRAOC2MAOA | |
| SCHEMBL5847146 | 0.72 | HPGD (0.64) | HPGDTSHRHSP90AB1SMN1; SMN2NFKB1 | |
| SCHEMBL5109501 | 0.72 | HPGD (0.64) | HPGDTSHRHSP90AB1SMN1; SMN2NFKB1 | |
| SCHEMBL1519327 | 0.72 | HPGD (0.64) | HPGDTSHRHSP90AB1SMN1; SMN2NFKB1 | |
| SCHEMBL8036060 | 0.71 | SSTR4 (0.43) | SSTR4HIF1AAOC2MAOAMAOB | |
| SCHEMBL2152425 | 0.71 | SSTR4 (0.36) | SSTR4HPGDTSHRHIF1AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060668-A1 | N-carboxyalkyl dipeptide derivatives and pharmaceutical compositions thereof | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |