Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28994581 | 0.81 | AOC3 (0.62) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL8375755 | 0.78 | AOC3 (0.62) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL7196888 | 0.78 | AOC3 (0.62) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL7678226 | 0.78 | ALDH1A1 (0.46) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL28300884 | 0.78 | ALDH1A1 (0.46) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| Iodide SCHEMBL25290234 | 0.77 | AOC3 (0.65) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL27725912 | 0.76 | AOC3 (0.56) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10869025 | 0.76 | MTNR1A (0.48) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL614836 | 0.75 | CYP2C9 (0.43) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL14876596 | 0.75 | AOC3 (0.59) | AOC3CYP2C9CYP2C19CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102030808-A | Tea saponin derivative with anti-inflammatory analgesic efficacy, preparation method and application thereof | UNIV SOUTH CHINA TECH | 2011-04-27 | — | — | CN | claimed |
| CN-102030808-B | Tea saponin derivative with anti-inflammatory analgesic efficacy, preparation method and application thereof | UNIV SOUTH CHINA TECH | 2013-04-10 | — | — | CN | disclosed |
| CN-102030808-A | Tea saponin derivative with anti-inflammatory analgesic efficacy, preparation method and application thereof | UNIV SOUTH CHINA TECH | 2011-04-27 | — | — | CN | disclosed |
| US-5047397-A | Natriuretics, diuretics, vasodilators | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0410989-A4 | CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0410989-A1 | CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES | CALIFORNIA BIOTECHNOLOGY, INC. (US) | 1991-02-06 | — | — | EP | disclosed |
| US-4935492-A | Cyclic analogs of atrial natriuretic peptides | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1990-06-19 | — | — | US | disclosed |
| WO-1989009611-A1 | CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0323740-A2 | Linear analogs of atrial natriuretic peptides | CALIFORNIA BIOTECHNOLOGY, INC. (US) | 1989-07-12 | — | — | EP | disclosed |
| WO-1989005654-A1 | LINEAR ANALOGS OF ATRIAL NATRIURETIC PEPTIDES | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1989-06-29 | — | — | WO | disclosed |