SCHEMBL8375755

SCHEMBL8375755

[CH2]CC(OC)c1cccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.62
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRA2A P08913 4/20 0.43
ADRA2B P18089 4/20 0.43
ADRA2C P18825 4/20 0.43
SLC6A4 P31645 3/20 0.41
SLC6A2 P23975 1/20 0.38
TSHR P16473 1/20 0.37
ADRA1A P35348 2/20 0.36
ACP3 P15309 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1B P35368 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994581 0.82 AOC3 (0.62) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL7196888 0.82 AOC3 (0.62) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
Iodide SCHEMBL25290234 0.81 AOC3 (0.65) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL15750826 0.79 AOC3 (0.59) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL14876596 0.79 AOC3 (0.59) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL29481516 0.79 AOC3 (0.59) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL4480225 0.79 AOC3 (0.59) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL7279503 0.78 AOC3 (0.57) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL9066103 0.77 ALDH1A1 (0.52) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL8375794 0.77 AOC3 (0.43) AOC3ALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110249004-A Polyimide precursor composition 东京应化工业株式会社 2019-09-17 CN disclosed
CN-108389512-A The manufacturing method of laminated body, flexible devices and laminated body 东京应化工业株式会社 2018-08-10 CN disclosed
CN-108387954-A The manufacturing method of laminated body, flexible devices and laminated body 东京应化工业株式会社 2018-08-10 CN disclosed
CN-108250754-A Containing silicone resin composition, containing silicone resin film, silica membrane, illuminated display element panel and luminous display unit 东京应化工业株式会社 2018-07-06 CN disclosed
CN-107922733-A Polyimide precursor composition 东京应化工业株式会社 2018-04-17 CN disclosed
CN-107429059-A ENERGY-SENSITIVE RESIN COMPOSITION 东京应化工业株式会社 2017-12-01 CN disclosed
US-6005116-A HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA SANKYO COMPANY, LIMITED (JP) 1999-12-21 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed