Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7271985 | 0.99 | GRIN2B (0.59) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| SCHEMBL7279623 | 0.88 | ADRA1A (0.54) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL7281334 | 0.87 | ADRA1A (0.53) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| SCHEMBL7272687 | 0.84 | ADRA1A (0.58) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| SCHEMBL7272848 | 0.84 | DRD2 (0.60) | GRIN2BSIGMAR1ADRA1ADRD3GRIN1 | |
| SCHEMBL7271830 | 0.83 | DRD2 (0.52) | GRIN2BSIGMAR1DRD1DRD3FYN | |
| Bromide SCHEMBL7281378 | 0.83 | DRD2 (0.59) | GRIN2BSIGMAR1ADRA1ADRD3GRIN1 | |
| SCHEMBL7270896 | 0.83 | ADRA1A (0.65) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL7270494 | 0.83 | ADRA1A (0.57) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 | |
| SCHEMBL7270986 | 0.83 | ADRA1A (0.65) | GRIN2BSIGMAR1ADRB2ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | claimed |