Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276191 | 0.82 | MAPT (0.57) | TRIM24TRIM33MAPTHTTDHODH | |
| SCHEMBL9402417 | 0.81 | GRM4 (0.43) | TRIM24TRIM33MAPTHTTERN1 | |
| SCHEMBL10678813 | 0.81 | MAPK14 (0.46) | TRIM24TRIM33MAPTHTTDHODH | |
| SCHEMBL10682704 | 0.77 | ERN1 (0.43) | TRIM24TRIM33MAPTHTTERN1 | |
| SCHEMBL16627420 | 0.76 | ALDH1A1 (0.44) | TRIM24TRIM33MAPTHTTALDH1A1 | |
| SCHEMBL28824960 | 0.74 | MAPT (0.71) | MAPTHTTDHODHALDH1A1KMT2A | |
| SCHEMBL29898295 | 0.74 | MAPT (0.71) | MAPTHTTDHODHALDH1A1KMT2A | |
| SCHEMBL9402324 | 0.74 | DHODH (0.57) | TRIM24TRIM33MAPTDHODHKMT2A | |
| SCHEMBL16627413 | 0.73 | RAB9A (0.62) | TRIM24TRIM33MAPTDHODHALDH1A1 | |
| SCHEMBL1376342 | 0.71 | DHODH (0.56) | TRIM24TRIM33MAPTHTTDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214055-A | Analgesics, psychological disorders, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-05-25 | — | — | US | disclosed |
| US-5189045-A | Antiserotonine agent | ADIR ET COMPAGNIE (FR) | 1993-02-23 | — | — | US | disclosed |
| EP-0457686-A1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |