Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117576 | 0.76 | ALDH1A1 (0.67) | NR4A2ALDH1A1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL2049777 | 0.75 | MEN1 (0.60) | NR4A2CNR1CNR2KMT2AMEN1 | |
| SCHEMBL7271018 | 0.74 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL1855462 | 0.74 | NR4A2 (1.00) | NR4A2ALDH1A1SMN1; SMN2CNR1KMT2A | |
| SCHEMBL28264481 | 0.73 | NR4A2 (0.76) | NR4A2ALDH1A1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL2090257 | 0.73 | NR4A2 (0.76) | NR4A2ALDH1A1SMN1; SMN2CNR1CYP1A2 | |
| SCHEMBL7276531 | 0.72 | CNR1 (0.56) | ALDH1A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL1019578 | 0.71 | P2RX7 (0.77) | NR4A2ALDH1A1SMN1; SMN2CNR1KMT2A | |
| SCHEMBL2033984 | 0.70 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL14159256 | 0.70 | NR4A2 (0.71) | NR4A2ALDH1A1SMN1; SMN2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |