Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271018 | 0.86 | CNR1 (0.57) | CNR1CNR2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7276038 | 0.85 | CHRNB2 (0.58) | CNR1CNR2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2049777 | 0.77 | MEN1 (0.60) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL15363131 | 0.77 | ALDH1A1 (0.70) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL2033984 | 0.76 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL2430574 | 0.74 | NR4A2 (0.72) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL8802608 | 0.74 | CHRNB2 (0.57) | ALDH1A1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL7269463 | 0.74 | CYP2D6 (0.60) | ALDH1A1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL7269469 | 0.74 | CYP2D6 (0.60) | ALDH1A1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL7271039 | 0.74 | CYP2D6 (0.60) | ALDH1A1CHRNB2CHRNA5CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |