Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278807 | 0.99 | ACHE (0.43) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL8813977 | 0.91 | ABL1 (0.41) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL2311 | 0.84 | ITGB1 (0.43) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL2563 | 0.83 | ITGB1 (0.42) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL8808660 | 0.83 | KCNH2 (0.36) | ACHEALDH1A1GAAL3MBTL1CD274 | |
| SCHEMBL8808945 | 0.83 | S1PR1 (0.34) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL8808908 | 0.83 | MAOB (0.39) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL8806612 | 0.82 | MAOB (0.38) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL7270209 | 0.77 | LTB4R2 (0.45) | ACHEITGB1ITGA4MYCWDR5 | |
| SCHEMBL8485794 | 0.76 | ABL1 (0.42) | ACHEITGB1ITGA4MYCWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |