Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079126 | 0.87 | S1PR1 (0.35) | S1PR1HDAC1ACHEALDH1A1KDM4E | |
| SCHEMBL8813977 | 0.85 | ABL1 (0.41) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL7280200 | 0.83 | ACHE (0.44) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL8808660 | 0.82 | KCNH2 (0.36) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL8808908 | 0.82 | MAOB (0.39) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL7278807 | 0.82 | ACHE (0.43) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL8806612 | 0.82 | MAOB (0.38) | ACHEALDH1A1KDM4EHSD17B10CD274 | |
| SCHEMBL8806815 | 0.81 | ACHE (0.34) | ACHE | |
| SCHEMBL8807911 | 0.74 | TP53 (0.33) | ACHEALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL8911282 | 0.72 | LTB4R2 (0.34) | ACHEALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528762-B1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| EP-0528762-A1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA-GEIGY AG (CH) | 1993-02-24 | — | — | EP | disclosed |