Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291148 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRLMNAMAPTALDH1A1 | |
| SCHEMBL7290560 | 0.84 | MEN1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL7291138 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRLMNAMAPTALDH1A1 | |
| SCHEMBL11083984 | 0.81 | SLC6A9 (0.48) | TSHRMAPTALDH1A1NPSR1AGER | |
| SCHEMBL7277786 | 0.80 | SLC6A2 (0.44) | — | |
| SCHEMBL11077996 | 0.79 | SLC6A9 (0.45) | MAPTAGER | |
| SCHEMBL11089047 | 0.76 | AKR1B10 (0.41) | SMN1; SMN2TSHRMAPTALDH1A1TRPM8 | |
| SCHEMBL11083674 | 0.74 | KMT2A (0.48) | TSHRLMNAALDH1A1AGER | |
| SCHEMBL7286178 | 0.73 | MEN1 (0.46) | LMNAMAPTALDH1A1 | |
| SCHEMBL7286509 | 0.73 | KDM4E (0.47) | ALDH1A1NPSR1AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479950-A | Aroylaminoacid disulfides | USV PHARMACEUTICAL CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| US-4347246-A | Antihypertensive lactams | USV PHARMACEUTICAL CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0054936-A1 | Aroyl amino acids | USV PHARMACEUTICAL CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |