Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.50 |
| ▸ | F10 | P00742 | 8/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7273435 | 0.99 | ITGB3 (0.49) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7282861 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7284261 | 0.82 | HRH2 (0.44) | S1PR1NPC1LMNAPOLBTSHR | |
| SCHEMBL7401425 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7282031 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL8540990 | 0.81 | F10 (0.52) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7393156 | 0.81 | RAB9A (0.54) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7283900 | 0.80 | RAB9A (0.53) | ITGB3ITGA2BF10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7283867 | 0.80 | F10 (0.48) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL7283544 | 0.78 | F10 (0.51) | ITGB3ITGA2BF10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |