Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398279 | 0.94 | ITGB3 (0.62) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7397288 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL7280220 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7399049 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BPRSS1F10F2 | |
| Hydrochloric Acid SCHEMBL7273435 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7405707 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7402530 | 0.80 | LMNA (0.46) | ITGB3ITGA2BPRSS1F10F2 | |
| SCHEMBL7418954 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7664080 | 0.79 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7698285 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0715623-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | claimed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0715623-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |