Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80110 | 0.87 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL1669167 | 0.87 | THRB (0.48) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL29400205 | 0.87 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL15049648 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL28519356 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| Methane SCHEMBL27599096 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| Hydrochloric Acid SCHEMBL7258725 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL14831125 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL14831124 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| Hydrochloric Acid SCHEMBL301551 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063449-A | Method for synthesizing isoindolinone from olefin and iodophor | 南方医科大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-110573503-B | Pyrrole derivatives as PLK1 inhibitors | 圣提内尔肿瘤学有限公司 | 2023-03-17 | — | — | CN | disclosed |
| EP-2951177-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | Neomed Institute (CA) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014117274-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NEOMED INSTITUTE (CA) | 2014-08-07 | — | — | WO | disclosed |
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0054936-A1 | Aroyl amino acids | USV PHARMACEUTICAL CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |