Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271134 | 0.89 | CTSL (0.56) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL7271139 | 0.89 | CTSL (0.56) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL3330029 | 0.85 | CTSB (0.52) | CTSBCTSLCTSSCTSKALDH1A1 | |
| SCHEMBL7266686 | 0.85 | CTSB (0.52) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL24447908 | 0.83 | CTSL (0.50) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL8138447 | 0.83 | CTSL (0.50) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL4622697 | 0.81 | CTSK (0.67) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL28546631 | 0.81 | CTSK (0.67) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL22225460 | 0.81 | CTSK (0.61) | CTSBCTSLCTSSCTSKCASP1 | |
| SCHEMBL4800376 | 0.81 | CTSK (0.67) | CTSBCTSLCTSSCTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145951-A | Protected ologopeptides; treating aids | BAYER AKTIENGESELLSCHAFT, A CORP. OF GERMANY (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0437729-A2 | New peptides, procedure for their preparation and their use as a medicament, especially their use as medicament against retroviruses | BAYER AG (DE) | 1991-07-24 | — | — | EP | disclosed |