Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193610 | 0.82 | LMNA (0.52) | LTA4HL3MBTL1KDM4ETSHRLMNA | |
| SCHEMBL6192033 | 0.82 | HTR1A (0.42) | LTA4HCYP2D6KDM4E | |
| SCHEMBL3015826 | 0.77 | LTA4H (0.78) | LTA4H | |
| SCHEMBL4843675 | 0.77 | LTA4H (0.78) | LTA4H | |
| SCHEMBL6192476 | 0.77 | ACSL1 (0.44) | LTA4HKDM4ETSHRMAPT | |
| Hydrochloric Acid SCHEMBL4320101 | 0.76 | LTA4H (0.76) | LTA4H | |
| SCHEMBL4975539 | 0.75 | LTA4H (0.57) | LTA4HRECQL | |
| SCHEMBL6451095 | 0.75 | LTA4H (0.43) | LTA4HL3MBTL1CYP2D6KDM4ETSHR | |
| SCHEMBL6449880 | 0.75 | LTA4H (0.43) | LTA4HL3MBTL1CYP2D6KDM4ETSHR | |
| SCHEMBL4842649 | 0.75 | LTA4H (0.57) | LTA4HRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |