Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.62 |
| ▸ | YAP1 | P46937 | 3/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.60 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282956 | 0.91 | YAP1 (0.64) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7281620 | 0.88 | YAP1 (0.54) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7279791 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7280338 | 0.87 | GPR119 (0.51) | ITGB3ITGA2BYAP1GPR119MMP13 | |
| SCHEMBL7280760 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7281055 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7442795 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7313782 | 0.85 | YAP1 (0.63) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7282664 | 0.84 | YAP1 (0.72) | ITGB3ITGA2BYAP1GPR119 | |
| SCHEMBL7312363 | 0.83 | GPR119 (0.62) | ITGB3ITGA2BYAP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040317-A | AN ANTIAGGLOMERANTS USEFUL IN THE PREVENTION AND TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION | MERCK & CO., INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5658929-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0478363-B1 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0743302-A2 | Sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5292756-A | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1993019046-A1 | NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0478363-A2 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |