Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274585 | 0.95 | ITGB3 (0.42) | F10ITGB3ITGA2BITGAVSENP1 | |
| Hydrochloric Acid SCHEMBL7272974 | 0.89 | F10 (0.51) | F10ITGB3ITGA2BITGAV | |
| SCHEMBL7284946 | 0.88 | F10 (0.48) | F10ITGB3ITGA2BITGAV | |
| SCHEMBL7283245 | 0.87 | DRD2 (0.43) | F10HDAC1 | |
| Water SCHEMBL7273367 | 0.87 | F10 (0.45) | F10ITGB3ITGA2BITGAV | |
| SCHEMBL7283072 | 0.84 | ITGB3 (0.37) | F10ITGB3ITGA2BITGAVPTGIR | |
| SCHEMBL7274068 | 0.84 | KDM1A (0.42) | F10ITGB3ITGA2B | |
| SCHEMBL7276505 | 0.84 | F2 (0.41) | ITGB3ITGA2BHDAC1 | |
| Hydrochloric Acid SCHEMBL8882502 | 0.84 | ITGB3 (0.37) | F10ITGB3ITGA2BITGAVPTGIR | |
| Hydrochloric Acid SCHEMBL7282224 | 0.84 | PARP1 (0.39) | ITGB3ITGA2BITGAVTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |