Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276505 | 0.93 | F2 (0.41) | KDM1AF2HDAC2HDAC8HDAC6 | |
| SCHEMBL7272267 | 0.93 | F10 (0.41) | KDM1AHDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL7282394 | 0.88 | ITGB3 (0.44) | KDM1AHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL7284039 | 0.88 | ITGB3 (0.42) | KDM1AHDAC8HDAC6RAB9ANPC1 | |
| Water SCHEMBL7273367 | 0.88 | F10 (0.45) | F2ITGB3ITGA2BF10 | |
| SCHEMBL7282719 | 0.87 | KDM1A (0.38) | KDM1AITGB3ITGA2BCHRM4LMNA | |
| SCHEMBL7274533 | 0.86 | TSHR (0.40) | F2ITGB3ITGA2BLMNAMEN1 | |
| Water SCHEMBL7281948 | 0.86 | PPARG (0.41) | KDM1AF2ITGB3ITGA2BF10 | |
| SCHEMBL7274469 | 0.85 | LMNA (0.42) | F2HDAC2HDAC8HDAC6ITGB3 | |
| SCHEMBL7274776 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |