Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989005 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL8529057 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL2301202 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL27912989 | 0.88 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8750552 | 0.84 | MEN1 (0.36) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL4961940 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL7079195 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8740426 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL5651011 | 0.83 | MEN1 (0.47) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8666244 | 0.82 | MEN1 (0.46) | MEN1GAAKMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044523-B | Dexamethasone-RGD polypeptide conjugate, preparation method thereof and application | JINAN XIANGHUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | claimed |
| CN-103012553-B | Cortisone-RGD polypeptide conjugate, and preparation method and application thereof | JINAN XIANGHUI MEDICAL TECHNOLOGY CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-103044523-A | Dexamethasone-RGD polypeptide conjugate, preparation method thereof and application | JINAN XIANGHUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-103012554-A | Hydrocortisone-RGD polypeptide conjugate, and preparation method and application thereof | SHANDONG BAYONN PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-103012553-A | Cortisone-RGD polypeptide conjugate, and preparation method and application thereof | JINAN XIANGHUI MEDICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-103044523-B | Dexamethasone-RGD polypeptide conjugate, preparation method thereof and application | JINAN XIANGHUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-103012553-B | Cortisone-RGD polypeptide conjugate, and preparation method and application thereof | JINAN XIANGHUI MEDICAL TECHNOLOGY CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102807601-B | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2014-02-26 | — | — | CN | disclosed |
| CN-103044523-A | Dexamethasone-RGD polypeptide conjugate, preparation method thereof and application | JINAN XIANGHUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-103012554-A | Hydrocortisone-RGD polypeptide conjugate, and preparation method and application thereof | SHANDONG BAYONN PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-103012553-A | Cortisone-RGD polypeptide conjugate, and preparation method and application thereof | JINAN XIANGHUI MEDICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-102807601-A | Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-12-05 | — | — | CN | disclosed |
| US-4204991-A | Sarcosine1 dehydroalanine8 angiotensin II derivatives | G. D. SEARLE & CO. (US) | 1980-05-27 | — | — | US | disclosed |
| US-4187217-A | HYPOTENSIVE AGENT OF PROLONGED EFFECT | CHIPENS GUNAR I (SU) | 1980-02-05 | — | — | US | disclosed |
| US-4171299-A | ANTIHISTAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1979-10-16 | — | — | US | disclosed |
| US-4161522-A | OLIGOPEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1979-07-17 | — | — | US | disclosed |
| US-4152322-A | PROCESS FOR SELECTIVE REDUCTION OF NITROARGINYL PEPTIDES WITH TITANIUM (III) | MERCK & CO., INC. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |
| US-4081533-A | INHIBITION OF LUTENIZING HORMONE, USING A NONAPEPTIDE, 8-ARGINE-VASOTOCIN, OR A TRIPEPTIDE, PROPYL-ARGINYL-GLYCINAMIDE | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1978-03-28 | — | — | US | disclosed |
| US-3974135-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same | FOLKERS KARL | 1976-08-10 | — | — | US | disclosed |