Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280716 | 0.84 | MEN1 (0.41) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL2301202 | 0.84 | MEN1 (0.41) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8529057 | 0.84 | MEN1 (0.41) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL12989005 | 0.84 | MEN1 (0.41) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL7079195 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL4961940 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8740426 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL27912989 | 0.80 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL11019775 | 0.74 | MAPT (0.39) | MEN1GAAKMT2A | |
| SCHEMBL7278004 | 0.72 | CA14 (0.34) | MEN1GAAKMT2ACA14TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765340-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-04-02 | — | — | EP | disclosed |