Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989005 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL2301202 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL7280716 | 1.00 | MEN1 (0.41) | MEN1GAAKMT2ANOS3NOS1 | |
| SCHEMBL27912989 | 0.88 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8750552 | 0.84 | MEN1 (0.36) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL4961940 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL7079195 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8740426 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL5651011 | 0.83 | MEN1 (0.47) | MEN1GAAKMT2ACA14MAOA | |
| SCHEMBL8666244 | 0.82 | MEN1 (0.46) | MEN1GAAKMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |