Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL305323 | 0.79 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL2919214 | 0.79 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL4755513 | 0.79 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL7289849 | 0.79 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| SCHEMBL15016003 | 0.79 | MMP8 (0.56) | SLC1A3SLC1A2SLC1A1MMP8SRR | |
| SCHEMBL27622664 | 0.79 | MMP8 (0.56) | SLC1A3SLC1A2SLC1A1MMP8SRR | |
| SCHEMBL7777115 | 0.77 | LTA4H (0.61) | — | |
| SCHEMBL15015720 | 0.77 | KMT2A (0.60) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| SCHEMBL5083632 | 0.77 | KMT2A (0.60) | SLC1A3SLC1A2SLC1A1SRRNPC1 | |
| SCHEMBL5083627 | 0.77 | KMT2A (0.60) | SLC1A3SLC1A2SLC1A1SRRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |