Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | CPA1 | P15085 | 2/20 | 0.58 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPA3 | P15088 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517132 | 0.81 | LTA4H (0.64) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL7280073 | 0.81 | CPA1 (0.57) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL7434721 | 0.81 | CPA1 (0.57) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL9226958 | 0.80 | CPA3 (0.64) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL11248580 | 0.79 | CPA3 (0.72) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL2398335 | 0.78 | CPA1 (0.66) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL901408 | 0.78 | CPA1 (0.66) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL1914987 | 0.78 | CPA1 (0.66) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL7280825 | 0.77 | SLC1A3 (0.54) | — | |
| SCHEMBL3842528 | 0.76 | CPA1 (0.64) | LTA4HCPA1CPB1CPA3CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129084-A2 | PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2001-09-05 | — | — | EP | claimed |
| WO-2000027832-A2 | THIAZOLE DERIVATIVES AS PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-05-18 | — | — | WO | claimed |
| EP-1129084-A2 | PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027832-A2 | THIAZOLE DERIVATIVES AS PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |