Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712690 | 0.83 | CA12 (0.44) | CA12GAAPOLBTDP1SMN1; SMN2 | |
| SCHEMBL344918 | 0.82 | MME (0.45) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL3488827 | 0.82 | MME (0.45) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL344919 | 0.82 | MME (0.45) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL23525156 | 0.80 | CA12 (0.42) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL4526295 | 0.80 | ALDH1A1 (0.50) | CA12CA9GAAPOLBTSHR | |
| Ammonia Solution, Strong SCHEMBL3276907 | 0.80 | MME (0.44) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL296053 | 0.80 | CA12 (0.42) | CA12CA9GAAPOLBTSHR | |
| SCHEMBL3385432 | 0.80 | FNTA (0.44) | CA12CA9GAAPOLBSMN1; SMN2 | |
| Methane SCHEMBL9693759 | 0.80 | MME (0.44) | CA12CA9GAAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4096180-A | Fluorodehydroxylation of serine | MERCK & CO., INC. (US) | 1978-06-20 | — | — | US | disclosed |