SCHEMBL296053

SCHEMBL296053

O=C(O)[C@H](C[SeH])Nc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
GAA P10253 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
TP53 P04637 1/20 0.40
EPHX1 P07099 1/20 0.40
EPHX2 P34913 1/20 0.40
CDK9 P50750 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
PPARG P37231 1/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX15 P16050 2/20 0.39
ALOX12 P18054 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23525156 1.00 CA12 (0.42) CA12CA9GAAPOLBMAPT
SCHEMBL28669122 0.98 CA12 (0.41) CA12CA9GAAPOLBMAPT
SCHEMBL344919 0.82 MME (0.45) CA12CA9GAAPOLBMAPT
SCHEMBL3488827 0.82 MME (0.45) CA12CA9GAAPOLBMAPT
SCHEMBL344918 0.82 MME (0.45) CA12CA9GAAPOLBMAPT
Water SCHEMBL4595531 0.80 MME (0.44) CA12CA9GAAPOLBMAPT
Ammonia Solution, Strong SCHEMBL3276907 0.80 MME (0.44) CA12CA9GAAPOLBMAPT
SCHEMBL3385432 0.80 FNTA (0.44) CA12CA9GAAPOLBMAPT
Methane SCHEMBL9693759 0.80 MME (0.44) CA12CA9GAAPOLBMAPT
SCHEMBL4526295 0.80 ALDH1A1 (0.50) CA12CA9GAAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025006976-A2 MRNA DISPLAY LIBRARIES AND METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-01-02 WO claimed
CN-113749275-B Electronic cigarette atomized liquid containing organic selenium compound 张家港外星人新材料科技有限公司 2024-02-06 CN claimed
EP-1994165-B1 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine SCRIPPS RESEARCH INST (US) 2014-11-05 EP claimed
US-8394605-B2 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2013-03-12 US claimed
US-20120282668-A1 Genetically Programmed Expression of Proteins Containing the Unnatural Amino Acid Phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2012-11-08 US claimed
US-8217145-B2 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPS RESEARCH INSTITUTE (US) 2012-07-10 US claimed
US-7790847-B2 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2010-09-07 US claimed
US-20090209000-A1 Genetically Programmed Expression of Proteins THE SCRIPPS RESEARCH INSTITUTE 2009-08-20 US claimed
EP-1994165-A2 GENETICALLY PROGRAMMED EXPRESSION OF PROTEINS CONTAINING THE UNNATURAL AMINO ACID PHENYLSELENOCYSTEINE The Scripps Research Institute (US) 2008-11-26 EP claimed
US-20070238152-A1 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2007-10-11 US claimed
WO-2007109035-A2 GENETICALLY PROGRAMMED EXPRESSION OF PROTEINS CONTAINING THE UNNATURAL AMINO ACID PHENYLSELENOCYSTEINE THE SCRIPPS RESEARCH INSTITUTE (US) 2007-09-27 WO claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 US disclosed
CN-122036912-A Cytokine conjugates for the treatment of proliferative and infectious diseases 辛索克斯公司 2026-05-15 CN disclosed
US-20260115295-A1 IMMUNO ONCOLOGY COMBINATION THERAPY WITH IL-2 CONJUGATES AND ANTI-EGFR ANTIBODIES Synthorx, Inc. (US) 2026-04-30 US disclosed
EP-4725953-A1 SELF-ASSEMBLING PEPTIDES AND HYDROGELS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-04-15 EP disclosed
US-20070238152-A1 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2007-10-11 US disclosed
US-20070238152-A1 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine THE SCRIPPS RESEARCH INSTITUTE (US) 2007-10-11 US disclosed
WO-2007109035-A2 GENETICALLY PROGRAMMED EXPRESSION OF PROTEINS CONTAINING THE UNNATURAL AMINO ACID PHENYLSELENOCYSTEINE THE SCRIPPS RESEARCH INSTITUTE (US) 2007-09-27 WO disclosed
WO-2007109035-A2 GENETICALLY PROGRAMMED EXPRESSION OF PROTEINS CONTAINING THE UNNATURAL AMINO ACID PHENYLSELENOCYSTEINE THE SCRIPPS RESEARCH INSTITUTE (US) 2007-09-27 WO disclosed
US-6579705-B2 Generating preferential amino acid sequences; obtain adjusted amino acid, incubate with enzyme, recover amino acid CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2003-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238152-A1 Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine NPEPPS, AARS1, NSUN3 CA12 4769/4885CA9 4557/4885GAA 1686/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 CA12 4676/4885CA9 4794/4885GAA 3170/4885
US-20090209000-A1 Genetically Programmed Expression of Proteins AARS1, COASY, NPEPPS CA12 4737/4885CA9 4541/4885GAA 1770/4885
US-20260115295-A1 IMMUNO ONCOLOGY COMBINATION THERAPY WITH IL-2 CONJUGATES AND ANTI-EGFR ANTIBODIES IL2, IL2RA, EGFR CA12 850/4885CA9 2126/4885GAA 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.