Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196579 | 0.84 | ALDH1A1 (0.47) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL7280942 | 0.83 | CA12 (0.42) | CA12POLBSMN1; SMN2TDP1MAPT | |
| SCHEMBL11195459 | 0.82 | CA12 (0.44) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL18360377 | 0.82 | MAPT (0.46) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL2322992 | 0.82 | ACE (0.45) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL11200746 | 0.81 | ALDH1A1 (0.51) | CA12CA1MMP8MAPTKMT2A | |
| SCHEMBL14850417 | 0.81 | CA12 (0.43) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL27485422 | 0.81 | FPR2 (0.50) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL14850405 | 0.81 | CA12 (0.43) | CA12CA1MMP8POLBSMN1; SMN2 | |
| SCHEMBL11200751 | 0.81 | ALDH1A1 (0.51) | CA12CA1MMP8MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384014-B1 | ANTIBIOTICS AS BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2002-05-07 | — | — | US | disclosed |