Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491330 | 1.00 | CTSK (0.47) | CTSKEPHX1ATMHPGDNPC1 | |
| SCHEMBL8364058 | 0.83 | CTSK (0.45) | CTSKEPHX1ATMHPGDNPC1 | |
| SCHEMBL9541732 | 0.83 | CTSK (0.45) | CTSKEPHX1ATMHPGDNPC1 | |
| SCHEMBL30314267 | 0.82 | CTSK (0.57) | CTSKEPHX1ATMHPGDACHE | |
| SCHEMBL5703708 | 0.82 | CTSK (0.57) | CTSKEPHX1ATMHPGDACHE | |
| SCHEMBL9425855 | 0.81 | SMN1; SMN2 (0.41) | CTSKATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL8382659 | 0.81 | EPHX1 (0.52) | EPHX1ATMHPGDNPC1RAB9A | |
| SCHEMBL7280943 | 0.80 | CTSK (0.57) | CTSKEPHX1ATMHPGDNPC1 | |
| SCHEMBL7040369 | 0.80 | CTSK (0.57) | CTSKEPHX1ATMHPGDNPC1 | |
| SCHEMBL8329646 | 0.80 | CTSK (0.43) | CTSKEPHX1ATMHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012076-A1 | REAGENTS FOR AUTOMATED SYNTHESIS OF PEPTIDE ANALOGS | CORVAS INTERNATIONAL INC. (US) | 1993-06-24 | — | — | WO | disclosed |