Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | CLTC | Q00610 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271538 | 0.85 | KDM4E (0.39) | CLTCCYP1B1USP2KMT2AKEAP1 | |
| SCHEMBL7271727 | 0.85 | CLTC (0.37) | CLTCCYP1B1USP2KMT2AKEAP1 | |
| Hydrochloric Acid SCHEMBL7277510 | 0.84 | KDM4E (0.38) | CLTCCYP1B1USP2KMT2AKEAP1 | |
| SCHEMBL9586964 | 0.80 | USP2 (0.57) | CYP1B1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL7279247 | 0.80 | HKDC1 (0.41) | HKDC1 | |
| SCHEMBL7709602 | 0.77 | HKDC1 (0.59) | HKDC1CLTCCYP1B1USP2KMT2A | |
| SCHEMBL7272077 | 0.75 | ERCC1 (0.49) | CYP1B1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11594529 | 0.71 | HKDC1 (0.63) | HKDC1CYP1B1USP2KMT2AKEAP1 | |
| SCHEMBL7271712 | 0.71 | MEN1 (0.61) | KMT2AMEN1ALDH1A1POLBCASP6 | |
| SCHEMBL7709795 | 0.69 | HKDC1 (0.65) | HKDC1CYP1B1USP2KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202318-A | Antiserotonine, antiemetic agents | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0457243-A1 | Novel tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |