SCHEMBL728158

SCHEMBL728158

ON1CCNc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 2/20 0.43
PIM1 P11309 1/20 0.40
BRD4 O60885 1/20 0.40
GAA P10253 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
BRPF1 P55201 1/20 0.39
HSD17B3 P37058 1/20 0.37
HSD11B1 P28845 1/20 0.36
MAPK1 P28482 1/20 0.36
GPBAR1 Q8TDU6 1/20 0.35
MMP2 P08253 2/20 0.35
ADRB1 P08588 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MMP9 P14780 1/20 0.33
ADAM17 P78536 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28328971 0.79 AVPR1A (0.40) AVPR1APIM1BRD4GAAMEN1
SCHEMBL8304937 0.78 BRPF1 (0.41) AVPR1ABRD4GAAMEN1KMT2A
SCHEMBL28833094 0.77 BRD4 (0.41) AVPR1APIM1BRD4GAAMEN1
SCHEMBL30463209 0.75 BRPF1 (0.47) AVPR1APIM1BRD4GAAMEN1
SCHEMBL3311949 0.75 AVPR1A (0.40) AVPR1APIM1BRD4GAAMEN1
SCHEMBL28330116 0.75 PIM1 (0.43) AVPR1APIM1BRD4GAAMEN1
SCHEMBL28886074 0.75 AVPR1A (0.40) AVPR1APIM1BRD4GAAMEN1
SCHEMBL305967 0.75 BRPF1 (0.47) AVPR1APIM1BRD4GAAMEN1
SCHEMBL19157283 0.75 AVPR1A (0.40) AVPR1APIM1BRD4GAAMEN1
SCHEMBL27934901 0.75 AVPR1A (0.40) AVPR1APIM1BRD4GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9103040-B2 Method of applying a magnesium-containing powder to the surface of an aluminum or aluminum alloy substrate NDSU RESEARCH FOUNDATION (US) 2015-08-11 US claimed
US-20140191163-A1 METHOD OF APPLYING A MAGNESIUM-CONTAINING POWDER TO THE SURFACE OF AN ALUMINUM OR ALUMINUM ALLOY SUBSTRATE NDSU RESEARCH FOUNDATION (US) 2014-07-10 US claimed
US-8568832-B2 Method of applying a magnesium-containing powder to the surface of an aluminum or aluminum alloy substrate NDSU RESEARCH FOUNDATION (US) 2013-10-29 US claimed
JP-4733643-B2 2011-07-27 JP claimed
JP-2007515550-A 2007-06-14 JP claimed
US-20070128351-A1 Magnesium rich coatings and coating systems AIR FORCE, UNITED STATES 2007-06-07 US claimed
EP-1689534-A4 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU RES FOUNDATION (US) 2007-04-04 EP claimed
EP-1689534-A1 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU Research Foundation (US) 2006-08-16 EP claimed
WO-2005051551-A1 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU RESEARCH FOUNDATION (US) 2005-06-09 WO claimed
US-9103040-B2 Method of applying a magnesium-containing powder to the surface of an aluminum or aluminum alloy substrate NDSU RESEARCH FOUNDATION (US) 2015-08-11 US disclosed
US-20140191163-A1 METHOD OF APPLYING A MAGNESIUM-CONTAINING POWDER TO THE SURFACE OF AN ALUMINUM OR ALUMINUM ALLOY SUBSTRATE NDSU RESEARCH FOUNDATION (US) 2014-07-10 US disclosed
US-8568832-B2 Method of applying a magnesium-containing powder to the surface of an aluminum or aluminum alloy substrate NDSU RESEARCH FOUNDATION (US) 2013-10-29 US disclosed
US-20070128351-A1 Magnesium rich coatings and coating systems AIR FORCE, UNITED STATES 2007-06-07 US disclosed
EP-1689534-A4 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU RES FOUNDATION (US) 2007-04-04 EP disclosed
EP-1689534-A1 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU Research Foundation (US) 2006-08-16 EP disclosed
WO-2005051551-A1 MAGNESIUM RICH COATINGS AND COATING SYSTEMS NDSU RESEARCH FOUNDATION (US) 2005-06-09 WO disclosed
US-4870171-A HYPOTENSIVE TOYO JOZO KABUSHIKI KAISHA (JP) 1989-09-26 US disclosed