Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292281 | 0.94 | HTR1A (0.65) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7278496 | 0.94 | HTR1A (0.61) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7284816 | 0.93 | HTR1A (0.55) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7291647 | 0.91 | HTR1A (0.51) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7281097 | 0.90 | HTR1A (0.50) | HTR1AHTR2AHTR1B | |
| SCHEMBL11243420 | 0.89 | HTR1A (0.69) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7282288 | 0.89 | HTR1A (0.59) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL11224419 | 0.89 | HTR1A (0.68) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7289134 | 0.88 | HTR1A (0.59) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7282326 | 0.88 | HTR1A (0.47) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |