Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288259 | 0.94 | DRD2 (0.59) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7281809 | 0.93 | HTR1A (0.63) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11351695 | 0.89 | HTR1A (0.60) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7282288 | 0.89 | HTR1A (0.59) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7289134 | 0.88 | HTR1A (0.59) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7282326 | 0.88 | HTR1A (0.47) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7288449 | 0.88 | HTR1A (0.58) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7280080 | 0.87 | HTR1A (0.58) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7292281 | 0.87 | HTR1A (0.65) | HTR1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6947219 | 0.86 | HTR1A (0.52) | HTR1AADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |