Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288815 | 0.91 | DRD2 (0.57) | HTR1ADRD2 | |
| SCHEMBL11242128 | 0.89 | SIGMAR1 (0.51) | HTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL7284816 | 0.88 | HTR1A (0.55) | HTR1ADRD2 | |
| SCHEMBL7281809 | 0.88 | HTR1A (0.63) | HTR1A | |
| SCHEMBL7288569 | 0.87 | DRD2 (0.49) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL7290976 | 0.85 | DRD2 (0.46) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL7291663 | 0.85 | HTR1A (0.52) | HTR1ADRD2DRD3SLC6A4HTR7 | |
| SCHEMBL7279846 | 0.84 | HTR1A (0.60) | HTR1ADRD2DRD4DRD3SLC6A4 | |
| SCHEMBL7281958 | 0.83 | HTR1A (0.46) | HTR1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL7282164 | 0.83 | HTR1A (0.58) | HTR1ADRD2DRD4DRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |