Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284980 | 0.96 | ITGB3 (0.58) | ITGB3ITGA2BHRH3KCNH2ACACB | |
| SCHEMBL7284195 | 0.94 | ITGB3 (0.57) | ITGB3ITGA2BHRH3KCNH2ACACB | |
| SCHEMBL7284255 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BMASP2 | |
| Lefradafiban SCHEMBL7080546 | 0.93 | ITGB3 (0.62) | ITGB3ITGA2BHRH3KDM4EIRAK4 | |
| Lefradafiban SCHEMBL50399 | 0.93 | ITGB3 (0.62) | ITGB3ITGA2BHRH3KDM4EIRAK4 | |
| SCHEMBL7281433 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BMASP2LTA4HPTPN1 | |
| SCHEMBL7311942 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BHRH3KCNH2ACACB | |
| SCHEMBL7312948 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KCNH2ACACB | |
| SCHEMBL8186359 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KCNH2MASP2 | |
| SCHEMBL7306622 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KCNH2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | claimed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |