Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304724 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4HRH3 | |
| SCHEMBL7282312 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7284980 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7311942 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7312948 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7284195 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7310130 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BIRAK4ACACBMASP2 | |
| SCHEMBL7281433 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BMASP2 | |
| SCHEMBL7283492 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7283791 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BIRAK4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |