Butylamine

Butylamine

SCHEMBL728279

CCCCN.O=P(O)(O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.65
GABBR1 Q9UBS5 3/20 0.65
GABRR1 P24046 1/20 0.65
TSHR P16473 2/20 0.52
CYP1A2 P05177 1/20 0.52
THPO P40225 1/20 0.52
FDPS P14324 3/20 0.52
DNM1 Q05193 4/20 0.50
LMNA P02545 2/20 0.50
BLM P54132 2/20 0.50
CYP3A4 P08684 1/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 1/20 0.50
EPHX1 P07099 1/20 0.50
SMPD1 P17405 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylamine SCHEMBL4299245 1.00 GABBR2 (0.65) GABBR2GABBR1GABRR1TSHRCYP1A2
Butylamine SCHEMBL21981126 1.00 GABBR2 (0.65) GABBR2GABBR1GABRR1TSHRCYP1A2
Butylamine SCHEMBL29194903 0.97 GABBR2 (0.62) GABBR2GABBR1GABRR1TSHRCYP1A2
Butylamine SCHEMBL28755797 0.97 GABBR2 (0.62) GABBR2GABBR1GABRR1TSHRCYP1A2
Butylamine SCHEMBL17784256 0.97 GABBR2 (0.62) GABBR2GABBR1GABRR1TSHRCYP1A2
Phosphoric Acid SCHEMBL30479420 0.92 DNM1 (0.63) GABBR2GABBR1GABRR1TSHRFDPS
Phosphoric Acid SCHEMBL1537957 0.92 DNM1 (0.63) GABBR2GABBR1GABRR1TSHRFDPS
Butylamine SCHEMBL10437182 0.92 GABBR2 (0.62) GABBR2GABBR1GABRR1TSHRCYP1A2
Butylamine SCHEMBL28113446 0.90 GABBR2 (0.56) GABBR2GABBR1GABRR1TSHRCYP1A2
Dodecylamine SCHEMBL23525472 0.89 DNM1 (0.68) GABBR2GABBR1GABRR1TSHRFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262552-A1 PURIFICATION OF GIP/ GLP-1 DUAL AGONIST PEPTIDES BIOCON LIMITED (IN) 2025-12-26 WO claimed
EP-3275039-B1 ELECTROLYTES AND METAL HYDRIDE BATTERIES BASF CORP (US) 2025-08-27 EP claimed
CN-118995291-B Preparation method and application of oil-soluble ionic liquid-carbon dot eutectic 中国科学院兰州化学物理研究所 2025-04-08 CN claimed
CN-118995291-A Preparation method and application of oil-soluble ionic liquid-carbon dot eutectic 中国科学院兰州化学物理研究所 2024-11-22 CN claimed
CN-107710462-B Electrochemical hydrogen storage electrode and battery 巴斯夫公司 2022-08-02 CN claimed
CN-107615556-B Electrolyte and metal hydride battery 巴斯夫公司 2021-11-02 CN claimed
US-10587012-B2 Electrolyte compositions comprising ionic liquids and metal hydride batteries comprising same BASF CORPORATION (US) 2020-03-10 US claimed
US-10243240-B2 Electrolytes and metal hydride batteries BASF CORPORATION (US) 2019-03-26 US claimed
EP-3292578-A1 ELECTROCHEMICAL HYDROGEN STORAGE ELECTRODES AND CELLS BASF Corporation (US) 2018-03-14 EP claimed
EP-3275039-A1 ELECTROLYTES AND METAL HYDRIDE BATTERIES BASF Corporation (US) 2018-01-31 EP claimed
EP-3218955-A1 ELECTROLYTES AND METAL HYDRIDE BATTERIES BASF Corporation (US) 2017-09-20 EP claimed
US-20160329560-A1 Electrochemical Hydrogen Storage Electrodes and Cells BASF CORPORATION (US) 2016-11-10 US claimed
US-20160285130-A1 Electrolytes and Metal Hydride Batteries U.S. DEPARTMENT OF ENERGY 2016-09-29 US claimed
US-20160141726-A1 Electrolytes and Metal Hydride Batteries BASF CORPORATION 2016-05-19 US claimed
US-20160141727-A1 Electrolytes and Metal Hydride Batteries BASF CORPORATION 2016-05-19 US claimed
CN-102246096-B Hardmask composition for forming etchant underlayer film and having improved storage stability CHEIL IND INC 2015-05-13 CN claimed
CN-102246096-A Hardmask composition for forming etchant underlayer film and having improved storage stability CHEIL IND INC 2011-11-16 CN claimed
US-5173341-A Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol TOKYO ROPE MFG. CO., LTD. (JP) 1992-12-22 US claimed
JP-10227779-A None JP disclosed
US-4510025-A ELECTROLYTIC OXIDATION OF TRICYCLENE AND CAMPHENE IN A LOWER FATTYACID KURARAY COMPANY, LTD. (JP) 1985-04-09 US disclosed