Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282687 | 0.83 | ACHE (0.52) | ELANEPARP1ACHEBCHEGRIN1 | |
| SCHEMBL8569514 | 0.64 | PARP1 (0.50) | ELANEPARP1DHODHCTRB1 | |
| SCHEMBL8075458 | 0.63 | ERN1 (0.46) | ELANEPARP1DHODHCTRB1 | |
| SCHEMBL27504633 | 0.62 | DHODH (0.44) | ELANEPARP1ACHEBCHEGRIN1 | |
| SCHEMBL8574209 | 0.62 | DHODH (0.54) | ELANEPARP1DHODH | |
| SCHEMBL6079712 | 0.61 | DHODH (0.47) | ELANEPARP1DHODH | |
| SCHEMBL10653208 | 0.60 | ACHE (0.58) | ELANEPARP1ACHEBCHEGRIN1 | |
| SCHEMBL6016106 | 0.60 | ELANE (0.44) | ELANEPARP1ACHEBCHEGRIN1 | |
| SCHEMBL480946 | 0.60 | ELANE (0.44) | ELANEPARP1ACHEBCHEGRIN1 | |
| SCHEMBL17866953 | 0.60 | ELANE (0.44) | ELANEPARP1ACHEBCHEGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |