Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.51 |
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283071 | 0.83 | ELANE (0.40) | ACHEBCHEGRIN1GRIN2AELANE | |
| SCHEMBL10350724 | 0.73 | ALDH1A1 (0.66) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10653208 | 0.71 | ACHE (0.58) | ACHEBCHEGRIN1GRIN2AELANE | |
| SCHEMBL10654771 | 0.69 | ACHE (0.63) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10651788 | 0.69 | ACHE (0.68) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10654258 | 0.69 | ACHE (0.68) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9583623 | 0.69 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL28700551 | 0.67 | ACHE (0.56) | ACHEBCHEGRIN1GRIN2AELANE | |
| SCHEMBL5391180 | 0.65 | ACHE (0.54) | ACHEBCHEGRIN1GRIN2AELANE | |
| SCHEMBL841926 | 0.64 | ACHE (0.53) | ACHEBCHEGRIN1GRIN2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |