Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983382 | 0.83 | AURKA (0.49) | ALDH1A1CCR8 | |
| SCHEMBL7299774 | 0.72 | CLEC4M (0.59) | ALDH1A1MAPTLMNA | |
| SCHEMBL3707647 | 0.70 | AKR1C3 (0.48) | ALDH1A1ATMMAPTNR4A1CYP2C8 | |
| SCHEMBL7291123 | 0.68 | CCR8 (0.50) | ALDH1A1CCR8LMNA | |
| SCHEMBL22955669 | 0.68 | F7 (0.71) | — | |
| SCHEMBL28157462 | 0.68 | NR4A1 (0.61) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL28287793 | 0.68 | F7 (0.61) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL11710855 | 0.67 | AKR1C2 (0.61) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL5962843 | 0.67 | MEN1 (0.56) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL29612638 | 0.66 | ALDH1A1 (0.63) | ALDH1A1MITFHSP90AA1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |