Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308147 | 0.81 | CYP1A2 (0.76) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL11200159 | 0.79 | CYP1A2 (0.62) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL11641095 | 0.76 | CYP1A2 (0.63) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL14037067 | 0.75 | ALDH1A1 (0.57) | CYP1A2CYP2C19CYP3A4GABRA1GABRB2 | |
| SCHEMBL16341803 | 0.74 | CLEC4M (0.78) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL30418194 | 0.74 | GABRA1 (0.74) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL1366633 | 0.74 | GABRA1 (0.74) | CLEC4MGABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL11647434 | 0.74 | CYP1A2 (0.52) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL11195663 | 0.74 | CLEC4M (0.78) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 | |
| SCHEMBL4300488 | 0.73 | CYP1A2 (0.63) | CLEC4MCYP1A2CYP2C19CYP3A4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |