Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208273 | 0.83 | GPR119 (0.34) | GPR119FAAH | |
| SCHEMBL4145435 | 0.81 | GPR119 (0.36) | GPR119POLBFAAH | |
| SCHEMBL18950459 | 0.81 | GPR119 (0.36) | GPR119POLBFAAH | |
| SCHEMBL5052785 | 0.81 | GPR119 (0.35) | GPR119FAAHHDAC3HDAC1HDAC2 | |
| SCHEMBL7283194 | 0.81 | GPR119 (0.33) | GPR119FAAH | |
| SCHEMBL2800325 | 0.80 | GPR119 (0.35) | GPR119POLBFAAH | |
| SCHEMBL2490063 | 0.80 | FAAH (0.43) | GPR119POLBFAAH | |
| SCHEMBL25736853 | 0.78 | GPR119 (0.32) | GPR119FAAHHDAC3HDAC1HDAC2 | |
| SCHEMBL6555078 | 0.78 | L3MBTL1 (0.35) | GPR119POLBFAAH | |
| SCHEMBL6172065 | 0.78 | GPR119 (0.35) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |