Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 17/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659999 | 0.89 | CYP3A4 (0.64) | ABCB1LMNAKMT2AUSP2ALDH1A1 | |
| SCHEMBL7291787 | 0.88 | LMNA (0.57) | ABCB1LMNAKMT2AUSP2ALDH1A1 | |
| Acetic Acid SCHEMBL7282924 | 0.88 | TSHR (0.61) | ABCB1LMNAKMT2AUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7292336 | 0.88 | LMNA (0.65) | ABCB1LMNAKMT2AALDH1A1TSHR | |
| SCHEMBL7283526 | 0.85 | L3MBTL1 (0.60) | ABCB1LMNAKMT2AUSP2TSHR | |
| SCHEMBL7288724 | 0.85 | LMNA (0.55) | ABCB1LMNAKMT2AUSP2ALDH1A1 | |
| SCHEMBL7289241 | 0.83 | KMT2A (0.58) | ABCB1LMNAKMT2AALDH1A1TP53 | |
| SCHEMBL10838014 | 0.83 | ABCB1 (0.51) | ABCB1LMNAKMT2AUSP2ALDH1A1 | |
| SCHEMBL10835718 | 0.82 | USP2 (0.64) | ABCB1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL7288758 | 0.82 | MAPT (0.53) | ABCB1LMNAKMT2AUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |