Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288514 | 0.87 | MAPT (0.57) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7282666 | 0.87 | RECQL (0.57) | MAPTLMNASMN1; SMN2KMT2AABCB1 | |
| SCHEMBL10838014 | 0.86 | ABCB1 (0.51) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7289241 | 0.84 | KMT2A (0.58) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL659999 | 0.84 | CYP3A4 (0.64) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7292235 | 0.84 | LMNA (0.49) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7292336 | 0.83 | LMNA (0.65) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7288724 | 0.82 | LMNA (0.55) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7283526 | 0.82 | L3MBTL1 (0.60) | LMNASMN1; SMN2MEN1KMT2AABCB1 | |
| SCHEMBL7283258 | 0.82 | ABCB1 (0.68) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |