Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281050 | 1.00 | NAMPT (0.41) | NAMPTLMNATSHRPOLBTRPV1 | |
| SCHEMBL7282882 | 0.96 | POLB (0.41) | NAMPTLMNATSHRPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8882333 | 0.88 | POLB (0.42) | NAMPTPOLBSIRT5HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL7283160 | 0.88 | POLB (0.42) | NAMPTPOLBSIRT5HDAC3HDAC1 | |
| SCHEMBL7283106 | 0.85 | SIGMAR1 (0.51) | NAMPTLMNATSHRPOLBHDAC3 | |
| SCHEMBL7273086 | 0.85 | SIGMAR1 (0.51) | NAMPTLMNATSHRPOLBHDAC3 | |
| Trifluoroacetic Acid SCHEMBL8881152 | 0.82 | SIGMAR1 (0.40) | POLBSIRT5HDAC3HDAC1HDAC2 | |
| SCHEMBL7284160 | 0.81 | SIGMAR1 (0.54) | LMNATSHRPOLBSIRT5HDAC3 | |
| SCHEMBL7272690 | 0.79 | NAMPT (0.41) | NAMPTLMNATSHRTRPV1L3MBTL1 | |
| SCHEMBL7284310 | 0.79 | NAMPT (0.41) | NAMPTLMNATSHRTRPV1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |