Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281706 | 0.90 | LTA4H (0.41) | ALDH1A1LMNAMAPTLTA4HSIGMAR1 | |
| SCHEMBL7275722 | 0.88 | SIGMAR1 (0.41) | ALDH1A1LMNAMAPTLTA4HSIGMAR1 | |
| SCHEMBL7282551 | 0.88 | ABCB1 (0.44) | ALDH1A1LMNAMAPTLTA4HOPRM1 | |
| SCHEMBL7281268 | 0.88 | ABCB1 (0.44) | ALDH1A1LMNAMAPTLTA4HOPRM1 | |
| SCHEMBL7274151 | 0.88 | ABCB1 (0.44) | ALDH1A1LMNAMAPTLTA4HOPRM1 | |
| Hydrochloric Acid SCHEMBL7283412 | 0.86 | ITGB3 (0.44) | ALDH1A1LMNAMAPTLTA4H | |
| Hydrochloric Acid SCHEMBL7281006 | 0.86 | ITGB3 (0.44) | ALDH1A1LMNAMAPTLTA4H | |
| Hydrochloric Acid SCHEMBL7283747 | 0.86 | LTA4H (0.38) | ALDH1A1LMNAMAPTLTA4H | |
| SCHEMBL7274458 | 0.85 | ABCB1 (0.43) | ALDH1A1LMNAMAPTLTA4HOPRM1 | |
| Hydrochloric Acid SCHEMBL7272807 | 0.84 | ITGB3 (0.43) | ALDH1A1LMNAMAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |