Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504209 | 0.80 | KDM4E (0.68) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL509578 | 0.79 | LOXL2 (1.00) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL3892437 | 0.77 | LOXL2 (0.65) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| Hydrochloric Acid SCHEMBL8135282 | 0.77 | LOXL2 (0.95) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL25210176 | 0.77 | LOXL2 (0.54) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| Hydrochloric Acid SCHEMBL30925271 | 0.77 | KDM4E (0.74) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL8698182 | 0.75 | KDM4E (0.47) | LOXL2KDM4ECYP3A4MAPTNOS1 | |
| SCHEMBL3497836 | 0.75 | KMT2A (0.59) | KDM4EMAPT | |
| SCHEMBL2323596 | 0.74 | BCHE (0.53) | MAPTCA2 | |
| SCHEMBL750418 | 0.74 | LOXL2 (0.88) | LOXL2KDM4ECYP3A4MAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |